Blar i forfatter "Pettersen, Kjell"

Viser treff 1-2 av 2

    • Associations of brain-natriuretic peptide, high-sensitive troponin T, and high-sensitive C-reactive protein with outcomes in severe aortic stenosis 

      Auensen, Andreas; Hussain, Amjad; Falk, Ragnhild Sørum; Walle-Hansen, Marte Meyer; Bye, Jorun; Pettersen, Kjell; Ueland, Thor; Gullestad, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-12)
      Objectives:<br>Among patients with severe aortic stenosis (AS), we investigated the associations of N–terminal pro–natriuretic peptide (NT–proBNP), high–sensitive troponin T (hsTnT), and high–sensitive C–reactive protein (hs–CRP) with 3–year mortality and major adverse cardiovascular events (MACE) during 1 year.<br>Methods:<br>This observational cohort study prospectively enrolled 442 patients with ...

    • Increased complement factor B and Bb levels are associated with mortality in patients with severe aortic stenosis 

      Shahini, Negar; Ueland, Thor; Auensen, Andreas; Michelsen, Annika; Ludviksen, Judith K; Hussain, Amjad Iqbal; Pettersen, Kjell; Aakhus, Svend; Espeland, Torvald; Lunde, Ida Gjervold; Kirschfink, Michael; Nilsson, Per; Mollnes, Tom Eirik; Gullestad, Lars; Aukrust, Pål; Yndestad, Arne; Louwe, Maria Cornelia (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-24)
      Inflammation is involved in initiation and progression of aortic stenosis (AS). However, the role of the complement system, a crucial component of innate immunity in AS, is unclear. We hypothesized that circulating levels of complement factor B (FB), an important component of the alternative pathway, are upregulated and could predict outcome in patients with severe symptomatic AS. Therefore, plasma ...